The differential clinical and neurocognitive profiles of COMT SNP rs165599 genotypes in schizophrenia
نویسندگان
چکیده
منابع مشابه
The differential clinical and neurocognitive profiles of COMT SNP rs165599 genotypes in schizophrenia.
متن کامل
Association study of single nucleotide polymorphism rs165599 of COMT gene, with schizophrenia and bipolar mood disorder in the south-west of Iran
Linkage studies and epidemiological findings indicate that some possible genes in schizophrenia (SCZ) and bipolar mood disorder (BPD) are common. Numerous evidences for linkage of two diseases on chromosome 22 have been found. These findings suggest that one or more genes in the 22q11.21 region may be involved in the development of both disorders. In the present case-control study, association ...
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Schizophrenia and bipolar disorder, although diagnostically separate, likely share elements of their genetic etiology. This study assessed whether the COMT Val158Met polymorphism has shared or specific associations with clinical phenotypes evident in schizophrenia and bipolar disorder. Schizophrenia and bipolar patients completed a clinical assessment encompassing premorbid functioning and curr...
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Schizophrenia, a severe psychiatric condition, is characterized by disturbances of cognition, emotion, and social functioning. The disease affects almost 1% of world population. Recent studies evaluating the role of catechol-O-methyltransferase enzyme (COMT) polymorphisms in the pathogenesis of schizophrenia have resulted in ambiguous findings. The current study examined the association of schi...
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ژورنال
عنوان ژورنال: Journal of the International Neuropsychological Society
سال: 2005
ISSN: 1355-6177,1469-7661
DOI: 10.1017/s1355617705050241